Doses reported by different users vary by a large amount, with some users reporting very strong effects from 50mg insufflated (heavy motor impairment, out of body experiences, etc), while others report 50mg insufflated causes much lighter effects (able to walk around mostly unimpaired, able to carry on lucid conversations, etc).

Many users find themselves taking two or more doses in a session/day.

Methoxetamine is a dissociative ketamine analog. It is most often found in powder form that is taken nasally, orally, injected intramuscalarly (IM), or used sublingually/buccaly. We have received two descriptions that sublingual is more potent than insufflated/intranasal, which is unusual for a drug, so we have updated the dosages to increase insufflated dosages, but this is all very tentative.

A number of reports indicate that oral dosages are similar to insufflated and buccal. Oral dosages for most drugs are normally higher (requiring more material to achieve the same effect), so this is an unusual result that will need to be confirmed over time and a larger number of uses.