Nicotine
Timeline
| Oct 12, 1492 | Christopher Columbus lands on the beaches of San Salvador in the West Indies and is offered fruit, wooden spears, and dried tobacco leaves by the natives. 1 | |
| 1556 | Andre Thevet brought the first tobacco (N. tabacum) to France from Brazil. 1 | |
| 1559 | Tobacco is dubbed "Nicotina" in honor of Jean Nicot, the French ambassador to Portugal, who sent it from Portugal to the French court as a medicine, beginning its spread in upper-class circles. 2 | |
| 1809 | Nicotine is first observed as an active product in tobacco juice by French scientist Vauguelin. | |
| 1828 | Nicotine is first isolated by Posselt and Reimann at the University of Heidelberg as the primary active ingredient in tobacco. They named it "Nicotine" in honor of Jean Nicot. | |
| 1856 | First British cigarette factory opens. 3 [Details] | |
| 1890 | My Lady Nicotine is published by Sir James Barrie in London. | |
| 1893 | The chemicals structure of nicotine is established by German chemist A. Pinner. 4 | |
| 1900 | Japan bans the use of cigarettes by anyone under the age of 20. 5 | |
| 1939 | German scientists propose a link between smoke inhalation and lung cancer. 5 | |
| 1967 | U.S. Federal Trade Commission releases first tar and nicotine report. 5 | |
| 1984 | Nicotine gum is first approved by the FDA for prescription use in the United States. | |
| 1992 | Nicotine patches are first approved by the FDA for prescription use in the United States. 5 | |
| 1996 | President Clinton announces a comprehensive anti-smoking program in the U.S. which includes granting the FDA jurisdiction to regulate cigarettes as nicotine delivery devices. | |
| Feb 1996 | Nicotine gum is approved for over-the-counter sale in the U.S. in February 1996. Soon thereafter, the nicotine patch is approved for over-the-counter sale in July. [More Info] |
References
- Heimann RK. Tobacco & Americans. McGraw-Hill, 1960.
- Austin G. "A Chronology of Psychoactive Substance Use".
- Lewine H. Good-Bye To All That. McGraw-Hill, 1970.
- Pinner A. Chem Ber.1893. 26;294.
- Farrington K. This is Nicotine. Sanctuary Pub, 2002.