Donate BTC or other Cryptocurrency
Your donation supports practical, accurate info about psychoactive
plants & drugs. We accept 9 cryptocurrencies. Contribute a bit today!
Anti-Depressant Microdosing
Syrian Rue & 5-HTP
Citation:   PinkFluffyUnicorns. "Anti-Depressant Microdosing: An Experience with Syrian Rue & 5-HTP (exp108918)". Erowid.org. Jul 28, 2016. erowid.org/exp/108918

 
DOSE:
  oral St. John's Wort (daily)
  100 mg oral Tryptophan - 5-HTP (daily)
  100 mg oral SAMe (daily)
  1 shot oral Syrian Rue (extract)
BODY WEIGHT: 70 kg
Today I started taking approx .25g daily of Syrian Rue as an alternative to pharmacological anti-depressants and as an adjunct to herbal ones. After major psychological trauma I was prescribed one after the other of SSRI's - all of which gave me horrific side effects.

I currently take St. Johns Wort (tincture) / 5HTP (100mg) / SAMe (100mg) but still needed something extra.
As Syrian Rue is an MAOI I am presuming it will potentiate the effects of the St. John's / 5HTP / SAMe.

I boiled 5grams of rue in 300mls of water for one hour then crushed the seeds as much as possible and strained and cooled. I ended up with 130 mls of rich yellow tincture that I took as 10ml shot.

After approx one hour I noticed a mild painkiller effect and I found I was fully engaged in what I was doing (whereas normally I feel a constant detachment from people and activities). After 4 hours I still feel more motivated than I have in months.

I plan to take my 20 doses that I boiled up tonight, 1 x day for the next 20 days then stop for a couple of weeks and see what happens. I really wish I could hear from others that might have done something similar.

Exp Year: 2016ExpID: 108918
Gender: Female 
Age at time of experience: 37
Published: Jul 28, 2016Views: 3,877
[ View PDF (to print) ] [ View LaTeX (for geeks) ] [ Swap Dark/Light ]
Syrian Rue (45), Tryptophan (138) : Alone (16), Therapeutic Intent or Outcome (49), Depression (15), General (1)

COPYRIGHTS: All reports copyright Erowid.
No AI Training use allowed without written permission.
TERMS OF USE: By accessing this page, you agree not to download, analyze, distill, reuse, digest, or feed into any AI-type system the report data without first contacting Erowid Center and receiving written permission.

Experience Reports are the writings and opinions of the authors who submit them. Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.


Experience Vaults Index Full List of Substances Search Submit Report User Settings About Main Psychoactive Vaults