DOSE:	36 mg	oral	Pharms - Methylphenidate
	10 mg	oral	Pharmaceuticals

BODY WEIGHT:

95 kg

Ritalin and Midodrine - Hypertensive Crisis

I have PoTS (postural tachycardia syndrome, secondary to EDS) and was prescribed midodrine for control of my labile blood pressure. After I was diagnosed with ADHD in Feb 22, I was started slowly on methylphenidate / Concerta XL. Close monitoring of my BP was performed.

After 4 weeks of relative stability; my BP rose uncontrollably resulting in a medical hypertensive crisis. My BP rose to > 180/120. I also had tachycardia, arrhythmias, headache, nausea, sweating and agitation.

This interaction has apparently NOT been documented in the Yellow Card scheme (UK). However, midodrine is a common prescribed drug for PoTS patients, who often use methylphenidate for comorbid ADHD and / or to stay alert.

Exp Year: 2022	ExpID: 116378
Gender: Female
Age at time of experience: 39
Published: Sep 26, 2022	Views: 405
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Pharms - Methylphenidate (114) : Combinations (3), Health Problems (27), Medical Use (47), Unknown Context (20)