DOSE: T+ 0:00	300 mg	oral	Adrafinil
T+ 0:59	300 mg	oral	Adrafinil
T+ 0:59	300 mg	oral	Adrafinil

BODY WEIGHT:

65 kg

As I read the following I thought, wow you should try this, seems not that neurotoxic like amphetamine.

From the Smart Drugs News, Vol.3, No.8: 'Adrafinil selectively stimulates alpha-1 adrenergic receptors, increasing alertness and sensory vigilance. Unlike other stimulants, such as amphetamines, Adrafinil does not cause anxiety and agitation, nor does it induce a need for 'rebound sleep.' Many other stimulants act as re-uptake inhibitors, increasing the levels of various neurotransmitters in the synapses. Adrafinil achieves its effect by binding to norepinephrine receptors directly, a very specific mode of action which greatly reduces the amount of unwanted side-effects. Moreover, the effect of this drug appears to be localized in the CNS, not stimulating the peripheral system to a significant degree.'

Well I took 300mg, and waited about one hour. Nothing. Took another Tbl. with 300mg. Again nothing. Then I thought, well take one more, and if its still inactive resell it to someone else. So I took another 300mg.

Waited, and waited, and the only thing that happened was, I was getting extremely tired, but was unable to sleep. Very unpleasant.

So my suggestion is, for everyone who searches for something that keeps you awake, take Yohimbine-HCL instead - Not Adrafinil. This medication is in my opinion totaly useless. No idea who put this on the pharma market.

-EOF

Exp Year: 2001	ExpID: 21397
Gender: Male
Age at time of experience: Not Given
Published: Mar 13, 2003	Views: 19,291
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Adrafinil (216) : General (1), Unknown Context (20)