DOSE:	8 mg	sublingual	Pharms - Buprenorphine	(daily)
	2 mg	sublingual	Naloxone	(daily)

Buprenorphine for Depression

I had what they call treatment-refractory depression. It means that all the regular medications didn't work. I've tried at least five different ones, including Cymbalta, Wellbutrin, Symbyax, Concerta, and Prozac. Not a single one of these did anything for me and most made me feel HORRIBLE. So I started self-medicating. Opioids were the ONLY thing that made me feel normal, but there are obviously a lot of drawbacks to the mu-agonists.

Eventually those drawbacks led me to an internist who prescribed Suboxone (buprenorphine/naloxone). It makes me feel just GOOD, but not like like an amphetamine or a cocaine good, just pleasant and positive, happy and calm. I have to stress, it is NOTHING at all like the amphetamines, its much more subtle.

I'm down to 8 mg/day now, and I can't remember what it was like to feel depressed. I've read that doses can go as low as 1 to 0.5 mg and still be effective for depression. I used to get a slight high from it, but my tolerance is up now and I just feel normal.

Exp Year: 2010	ExpID: 91263
Gender: Not Specified
Age at time of experience: Not Given
Published: Jun 5, 2019	Views: 936
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Pharms - Buprenorphine (265) : Depression (15), Medical Use (47), Not Applicable (38)