Naloxone
COMMON & BRAND NAMES
Narcan; Nalone; Narcanti; Suboxone (w/buprenorphine)
EFFECTS CLASSIFICATION
Narcotic detoxification adjunct
CHEMICAL NAME
17-allyl-4,alpha-epoxy- 3,14-dihydroxymorphinan-6-one
DESCRIPTION
Naloxone is an opioid antagonist used to counter the effects of opioid overdose, particularly respiratory suppression. It rapidly displaces opioids such as heroin from binding sites in the brain, causing an almost-immediate cessation of drug effects.
GENERAL INFORMATION #
Tolerance, Addiction, and Effective Pain Management, by K. Trout
RESEARCH & JOURNAL ARTICLES #
ASK EROWID ANSWERS #
EXPERIENCES #
A Look for the Opiate User, by FamousRoger
Recovering From Severe Opiate Addiction, by xdefeatsy
Seeds of Addiction, by Noz
OFF-SITE RESOURCES
MEDIA COVERAGE #
Why the Inventor of the Antidote Naloxone Lost His Stepson to Heroin - Newsweek, June 5 2016
Prince’s Death Spotlights Overdose Antidote Dilemma - Wall Street Journal, May 11 2016
B.C. sees huge increase in use of Naloxone to reverse drug overdoses - CKNW (Vancouver), Apr 25 2016
Using Naloxone (Narcan) As A Last Resort - Forbes, Apr 17 2016
Price Soars For Key Weapon Against Heroin Overdoses - Sep 10 2015, NPR
Overdose Rescue Kits Save Lives - Jan 2 2008, NPR
Emergency Antidote, Direct to Addicts - New York Times, Dec 11 2007
GOVERNMENT RESOURCES #
FDA approves first generic naloxone nasal spray to treat opioid overdose - US FDA, April 19, 2019
New EMCDDA insights into naloxone (Jan 2016)