Erowid References Database
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Freter K, Axelrod J, Witkop B.
“Studies on the chemical and enzymatic oxidation of lysergic acid diethylamide.”.
J. Amer.Chem. Soc.. 1957;79:3191.
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Abstract
The formation, by enzymatic oxidation, of a physiologically inactive metabolite of LSD has been previously reported (Axelrod et al., Nature 178: 143, 1956). . The trichloroacetate of LSD reacts with disulphur dichloride in benzene to yield a disulphide which, by reductive hydrolysis, gives a compound identical with the metabolite obtained by enzymatic oxidation.
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