Erowid.org: Erowid Reference 1885 : Interaction of lysergic acid diethylamide (LSD) with polypeptides which stimulate smooth muscle : Smith CM, Walaszek EJ

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Smith CM, Walaszek EJ. “Interaction of lysergic acid diethylamide (LSD) with polypeptides which stimulate smooth muscle”. Fed. Proc.. 1960;19:264. <a name="ref">Smith CM, Walaszek EJ.</a> <a href="/references/1885">"Interaction of lysergic acid diethylamide (LSD) with polypeptides which stimulate smooth muscle"</a> <i>Fed. Proc.</i>. 1960;19:264.
Show Articles by Smith CM Walaszek EJ Article IDs LSDID: 0776 Erowid RefID: 1885 PubMedID: unknown Collections Hofmann Collection MDMA Collection All References	Abstract LSD in concentration of 0.03-0.1 mcg/ml potentiates the stimulating effect of substance P, substance A and bradykinin on the smooth muscle (isolated guinea pig ileum). . LSD was added to the organ bath 2 minutes before the addition of the mentioned polypeptides. In concentrations higher than 0.1 mcg/ml LSD gave a stimulating effect of its own. Other hallucinogens were unable to potentiate the stimulating effect of substance P. . "It is concluded that this potentiation by LSD probably bears no relationship to its hallucinogenic properties and the mechanism of potentiation is probably due to the inhibitory effect of LSD on enzymes capable of inactivating polypeptides."
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