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Vojtechovsky M, Horácková E, Grof S.
“Pokus o blokováni experimentální psychózy po LSD-25 theadrylem. ”.
Csl. Psychiat.. 1960;56:34-43.
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Abstract
In 3 healthy subjects an attempt was made to block LSD psychoses by theadryl (Dramamine). Theadryl has proved of value in the therapy of acute psychoses. . The first subject received as premedication 300 mg. theadryl within 12 hours, thereafter 100 mcg. LSD together with 100 mg. theadryl. The second subject received as premedication 750 mg. theadryl within 72 hours, thereafter 100 mcg. LSD together with 100 mg. theadryl. The third subject received as premedication 750 mg. theadryl within 72 hours, thereafter 150 mcg. LSD. . The clinical observations and experimental psychological methods of examination during the model psychosis did not give convincing evidence of a blocking action by theadryl. In the first case theadryl changed the picture of the LSD psychosis mainly in the emotional sphere, it was 40-50% quantitatively reduced. In the second and third cases, theadryl premedication worsened the subjective experience of the LSD psychosis, thus a qualitatively new picture arose in contract to the previous LSD psychoses with disturbances of the body-image, fatigue and attacks of dizziness.
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