Erowid References Database
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Messier PE.
“Effects of LSD on the Development, Histology and Fine Structure of the Chick Embryo”.
Toxicol Appl Pharmacol. 1973;25:54-59.
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Abstract
Chick embryos cultured in vitro were exposed to LSD in concentrations of 0.0005, 0.005, 0.05, 0.5 and 2.5 mcg/ml. The two highest concentrations retarded the segmentation- of mesoderm into somites and caused a comcgpse of the roof of the neural tube. Electron microscopy showed that nucleolar components were segregated and that mitochondria were altered following the treatment. Doses of 0.005 and 0.05 mcg/ml produced similar abnormalities but in fewer cases. The lowest concentration used produced no changes in the embryos.
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