Erowid.org: Erowid Reference 2835 : The Influence Of Cyproheptadine And Of D-lysergamide On The Rise In Temperature Induced By Intracerebroventicular 5-hydroxytryptamine, Noradrenaline And Dopamine In Conscious Rabbits : Jacob JJ, Girault JMT

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Jacob JJ, Girault JMT. “The Influence Of Cyproheptadine And Of D-lysergamide On The Rise In Temperature Induced By Intracerebroventicular 5-hydroxytryptamine, Noradrenaline And Dopamine In Conscious Rabbits”. Eur J Pharmacology. 1974;27:59-67. <a name="ref">Jacob JJ, Girault JMT.</a> <a href="/references/2835">"The Influence Of Cyproheptadine And Of D-lysergamide On The Rise In Temperature Induced By Intracerebroventicular 5-hydroxytryptamine, Noradrenaline And Dopamine In Conscious Rabbits"</a> <i>Eur J Pharmacology</i>. 1974;27:59-67.
Text Abstract (this page) Full Text - English (814 K) Show Articles by Jacob JJ Girault JMT Article IDs LSDID: 2551 Erowid RefID: 2835 PubMedID: unknown Collections Hofmann Collection MDMA Collection All References	Abstract Cyproheptadine and LSD, two known antagonists of the peripheral effects of 5-HT, were administered i.v. to conscious rabbits at different times before the intracerebroventricular (i.c.v.) administration of 5-HT, NAD or dopamine. Cyproheptadine (which had a slight hypothermic effect) antagonized the rise in temperature induced by 5 - HT; this antagonism was dose-related and appeared to be specific in that the hyperthermia induced by noradrenaine or dopamine was hardly modified. Interactions between LSD (which is hyperthermic alone) and 5-HT were more complex - both potentiation and depression being observed.
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