Erowid.org: Erowid Reference 2885 : Effect of LSD-25 and l-Methyl-d-Lysergic Acid Butanolamide on Rat Brain and Platelet Serotonin Levels : Torre M, Bogetto F, Torte E

Erowid References Database

Torre M, Bogetto F, Torte E. “Effect of LSD-25 and l-Methyl-d-Lysergic Acid Butanolamide on Rat Brain and Platelet Serotonin Levels”. Psychopharmacologia (Berl). 1974;36:117-122. <a name="ref">Torre M, Bogetto F, Torte E.</a> <a href="/references/2885">"Effect of LSD-25 and l-Methyl-d-Lysergic Acid Butanolamide on Rat Brain and Platelet Serotonin Levels"</a> <i>Psychopharmacologia (Berl)</i>. 1974;36:117-122.
Text Abstract (this page) Full Text - English (504 K) Show Articles by Torre M Bogetto F Torte E Article IDs LSDID: 2603 Erowid RefID: 2885 PubMedID: unknown Collections Hofmann Collection MDMA Collection All References	Abstract Factorial analysis of rat cerebral 5-HT values observed following intraperitoneal LSD-25 and U3IL (1-methyl-d-lysergic acid butanolamide) showed that the highly significant decrease induced by both drugs was independent of dose and that the effect of both drugs was the same. Increased platelet 5-HT values were also obtained with each drug. These findings suggest that the psychotomimetic effect of LSD-25 is not due to changes in cerebral 5-HT, since a relationship can probably be postulated between such an effect-in man and the effect of LSD-25 on conditioned behaviour in the rat. It is also fel' that the feet that these drugs decrease and increase cerebral and platelet values respectively may be of assistance in the interpretation of data relating to platelet 5-HT patterns in man Under psychiatric conditions and during treatment with psychotropic drugs.
Comments and Responses to this Article #
Submit Comment

[ Cite HTML ]