Erowid References Database
Halaris AE, Freedman DX, Fang VS.
“Plasma Corticoids And Brain Tryptophan After Acute And Tolerance Dosage Of LSD”.
Life Sciences. 1975;17:1467-1472.
|
Abstract
The effect of acute and tolerance dosage schedules of LSD on plasma corticoids and brain tryptophan in normal, adren - alectomized and hypophysectomized rats was examined. Plasma corticoids increased 20-fold after one dose of LSD and the time course of this effect paralleled the increase in brain trypto - phan. Both effects of LSD were abolished in adrenalectomized animals; after hypophysectomy the drug-induced tryptophan increase did occur but only after a significant delay. After multiple daily injections of LSD there was a significant degree of toler - ance both to the plasma corticoid and brain tryptophan response.
|
# |
Submit Comment |
|
[
Cite HTML ]