Erowid References Database
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Sam V, Joseph T.
“Effect Of Lysergic Acid Diethylamide On Oestrus Cycle And Offspring In Rats”.
Indian J.Physiol.Pharmacol.. 1973;l7:277-282.
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Abstract
Lysergic acid diethylamide (LSD-25) was studied for its effect on oestrus cycle and offspring in rats. The drug in a single dose of mcg/kg so did not produce by any alteration in the normal four day oestrus cycle of rats. Though an oral dose of 200 mcg/kg given in early pregnancy did not produce any change in either litter size or foetal mortality rate, 100 and 200 mcg/kg sc given at a similar period of pregnancy decreased litter size, produced stunted foetuses, increased foetal mortality rate and the number of resorptions as evidenced by increase in vascularity and beading in the uteri of drug treated females. No unusual specific deformities were noticed in either live or dead foetuses.
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