Erowid References Database
Spaulding DC, Dewey WL.
“Interaction of the behaviorally active drug, phenitrone, a purported hashish and LSD antagonist, with several central neurochemical systems”.
Federation Proceedings. 1973;32(3):755.
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Abstract
At the 57th annual meeting of the Federation of American Societies for Experimental Biology, the interaction of the behaviorally active drug, phenitron (I), a purported hashish and LSD antagonist, with several central neurochemical systems was reported. Acetylcholine (Ach) response in the isolated-frog rectus abdominus was potentiated by small dose of I. The ' in vitro hydrolysis of acetylthiocholine and bu-tylthiocholine by rat whole brain homogenate was inhibited by I. Mouse whole brain levels of serotonin were lowered and serotonin turnover rate was decreased by I.- The data suggest that I, like many other centrally acting agonists and an-tagonists, affect more than one neurochemical - system in the brain. (Author-abstract modified)
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