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Kleinrok Z, Jagiello Wojtowicz E.
“The Central Action Of Intraventricular Hydroxytryptamine In The Rat”.
Ann. Univ. M. Curie-Sklodowska, Sec. D. 1975;30:277-283.
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Abstract
THE INFLUENCE CF 5 HT ADNINISTERED INTRAVENTRICULARLY ON THE BEHAVIOR OF RATS WAS INVESTIGATED. IT WAS FOUND THAT 5 HT IN DOSES 25, 50, 130 AND 250 UEG/RAT CAUSEG AN INHIBITION OF SPONTANEOUS LOCOMOTOR ACTIVITY, AN INHIBITION OF THE BEHAVIOR IN ÔOPEN FIELDÕ TESTS, AND A DECREASE IN BODY TEMPERATURE. 5 HT HAD NO INFLUENCE ON TEH ACTION OF NARCOTICS, ANALEPTICS, ELECTRIC CONVULSIONS AND AMPHETAMINE STEREOTYPY. BESIDES THIS, IT WAS FOUND THAT IN RATS PRETREATED WITH LSD-25, THE INHIBITORY ACTION OF 5-HT WAS UNCHANGED.
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