Erowid References Database
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West KB, Hernandez LL, Appel JB.
“Drugs and Visual Perception: Effects of LSD, Morphine and Chlorpromazine on Accuracy, Bias and Speed”.
Psychopharmacology. 1982;76(4):320-324.
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Abstract
Ten pigeons were trained to discriminate between the intensities of two white lights (projected behind a center response \"key\") using a discrete trial procedure in which choice behavior involved pecking at red or green lights projected behind left or right side keys. LSD (0.02-0.08 mg/kg) did not alter the accuracy of the brightness discrimination (percent correct) although it did lower response speed and may have differentially affected spatial (position) bias. Morphine (2.5 - 10.0 mg/kg) decreased accuracy of discrimination as well as response speed and had greater effects on trials when the bright stimulus was presented than when the dim stimulus was presented. Chlorpromazine (7.5 - 30.0 mg/kg) lowered accuracy without significantly altering any other measure of performance.
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