Erowid References Database
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Jaju BP, Srimal RC, Dhawan KN, Gupta GP.
“Effect of lysergic acid diethylamide (LSD25) on morphine induced bradycardia”.
Jap. J. Pharmacol.. 1967;17:678-680.
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Abstract
Several antagonistic interactions between morphine and LSD-25 (lysergic acid diethylamide) have been demonstrated. LSD-25 antagonizes morphine induced analgesia in rats (1) and emesis in dogs (2). It also blocks the miotic action of morphine (3). On the other hand morphine blocks LSD-25 induced pyrexia in rabbits (4) and the central hypotensive effect of LSD-25 in dogs (5). Morphine produces marked bradycardia in rabbits (6) and the present study was undertaken to see if LSD-25 antagonizes this effect of morphine as well.
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