Erowid References Database
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TRUITT EB, CALLAWAY E, BRAUDE MC, KRANTZ JC.
“The pharmacology of myristicin: a contribution to the psychopharmacology of nutmeg”.
J Neuropsychiatr. 1961 Apr 01;2:205-10.
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Abstract
The pharmacologic and toxic effects of myristicin have been examined in laborator animals in order to estimate its safety in man. Myristicin is assumed to be the principal active ingredient of nutmeg powder. In 400mg. doses, myristicin produced mild cerebral stimulation in human subjects. this effect is much less than that produced by 15mg of nutmeg powder, which was taken by one of the authors in order to describe its pharmacologic action. Removal of the volatile components of nutmeg eliminates the psychic action but not all of the side effects. It appears that myristicin does not reproduce the entire activities of whole nutmeg.
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