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Ghosal, S., Singh, S. and Bhattacharya, S.K..
“Alkaloids of Mucuna Pruriens Chemistry and Pharmacology”.
Planta Medica. 1971;19:279-84.
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Abstract
Mucuna pruriens DC. (Papilionaceae) which grows abundantly in India, finds use {Kirtikar and Basu, 1933) in the indigenous system of medicine for a variety of purposes, viz., as an uterine stimulant, in dysentery, as a nerve tonic, diuretic, and aphrodisiac.
Majumdar and Mehta (1944) previously reported the presence of alkaloids
in the seeds of this species but could not characterize them. Later, Bowden et al.
(1954) recorded evidence for the presence of serotonin in the trichomes of its
pods.
The incomplete phytochemical investigation and the reported uses of the plant
extracts in the indigenous system of medicine prompted the present authors to undertake a detailed phytochemical and pharmacological evaluation of this species. Various individual parts of the plant,,e. g., the seeds, pods, trichomes of pods, leaves, stems, and roots, were investigated separately for their"alkaloidI contents.The isolation,
characterization, and pharmacological evaluation of the alkaloids constitute the subject of the present paper.
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