Erowid References Database
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Ott J, Neely P.
“Entheogenic (hallucinogenic) effects of methylergonovine”.
J Psychedelic Drugs. 1980 Apr-Jun 18;12(2):165-6.
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Abstract
In a previous publication (Bigwood et al. 1979) we reported on entheogenic effects of ergonovine, the specific uterotonic, water-soluble principle of ergot, the sclerotium of Claviceps purpurea (Ft.) Tul. Ergonovine was isolated simultaneously by four different research groups in the mid-19 30s and designated variously ergobasine, ergometrine, ergotocine and ergostetrine. The drug was first synthesized in 1937 by Albert Hofmann of the Swiss pharmaceutical firm Sandoz Ltd., and its structure proved to be d-lysergic acid-L-2- propanolamide (Stoll & Hofmann 1943). Ergonovine found widespread application in obstetrics as a hemostatic remedy for control of post-partum hemorrhage. Despite its widespread use, the drug was not known to be entheogenic until Hofmann, in 1976,
ingested 2.0 mg of ergonovine maleate (the therapeutic dose normally employed is 0.2-0.4 mg) (Wasson, Hofmann & Ruck 1978).
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