Erowid References Database
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Bigwood J, Ott J, Thompson C, Neely P.
“Entheogenic effects of ergonovine”.
J Psychedelic Drugs. 1979 Jan-Jun 24;11(1-2):147-9.
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Abstract
In 1932 the English researchers C. Moir and H.W. Dudley determined that aqueous extracts of ergot, the sclerotium of the parasitic fungus Claviceps purpurea {Ft.) Tulasne, manifested a strong uterotonic activity (Moir 1932). Such activity had long been attributed to ergot, but previous investigations had established this only in water-insoluble constituents, such as ergotamine. In 1935 a novel water-soluble alkaloid having uterotonic properties was isolated from ergot by four different laboratories working independently (Hofmann 1964). A. Stoll and E. Burckhardt of the Swiss pharmaceutical
firm Sandoz named this alkaloid ergobasine (Stoll & Burckhardt 1935), Moir and Dudley called it ergo metrine, M.S. Kharasch and R.R. Legault designated it ergotocine and M.R. Thompson gave it the name ergostetrine. By agreement of the International Pharma
copoeia Commission, the name "ergonovine" was adopted to replace these synonyms.
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