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Jansen KL, Prast CJ. 
“Psychoactive properties of mitragynine (kratom)”. 
J Psychoactive Drugs. 1988 Oct-Dec 02;20(4):455-7.
Abstract
Mitragynine and several related alkaloids are derived from the leaves of Mitragyna speciosa (kratom), a tree that is found principally in Thailand and Malaysia. Despite their intriguing, contradictory psychoactive properties, possible medical applications and widespread use in Thailand, very little new research has appeared on these substances for over a decade (Jansen & Prast 1988).
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