Erowid.org: Erowid Reference 7718 : Salvinorin A: the 'magic mint' hallucinogen finds a molecular target in the kappa opioid receptor : Sheffler DJ, Roth BL

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Sheffler DJ, Roth BL. “Salvinorin A: the 'magic mint' hallucinogen finds a molecular target in the kappa opioid receptor”. Trends Pharmacol Sci. 2003 Mar 11;24(3):107-9. <a name="ref">Sheffler DJ, Roth BL.</a> <a href="/references/7718">"Salvinorin A: the 'magic mint' hallucinogen finds a molecular target in the kappa opioid receptor"</a> <i>Trends Pharmacol Sci</i>. 2003 Mar 11;24(3):107-9.
Text Abstract (this page) Full Text - English (private) Show Articles by Sheffler DJ Roth BL Article IDs Erowid RefID: 7718 PubMedID: 12628350 Collections Hofmann Collection MDMA Collection All References	Abstract Salvinorin A, a neoclerodane diterpene, is the most potent naturally occurring hallucinogen known and rivals the synthetic hallucinogen lysergic acid diethylamide in potency. Recently, the molecular target of salvinorin A was identified as the kappa opioid receptor (KOR). Salvinorin A represents the only known non-nitrogenous KOR selective agonist. Based on the selectivity of salvinorin A for the KOR, this receptor represents a potential molecular target for the development of drugs to treat disorders characterized by alterations in perception, including schizophrenia, Alzheimer's disease and bipolar disorder.
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