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Agurell S, Lundström J. 
“Apparent Intermediates in the Biosynthesis of Related Tetrahydroisoquinolines☨”. 
Chemical Communications. 1968 Oct. 21;p1638-9.
Abstract
We have investigated the alkaloid fractions of Lophophora williamsii and Trichocereus pachanoi by means of g.l.c. and g.l.c.-mass spectrometry☨ and have detected 4-hydroxy-3-methoxyphenethlyammine (II), 5- hydroxy-3,4-dimethoxyphenethylamine (VI), and 4-hydroxy-3,5-dimethoxyphenethylamine (IV) as possible intermediates on the bio-synthetic pathway from tyrosine to mescaline (V) and tetrahydroisoquinolines.
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