Erowid.org: Erowid Reference 7916 : Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594 : Zhang CX, Ge ZM, Cheng TM, Li RT

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Zhang CX, Ge ZM, Cheng TM, Li RT. “Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594”. Bioorg Med Chem Lett. 2006 Apr 27;16(7):2013-6. <a name="ref">Zhang CX, Ge ZM, Cheng TM, Li RT.</a> <a href="/references/7916">"Synthesis and analgesic activity of secondary amine analogues of pyridylmethylamine and positional isomeric analogues of ABT-594"</a> <i>Bioorg Med Chem Lett</i>. 2006 Apr 27;16(7):2013-6.
Text Abstract (this page) Full Text - English (private) Show Articles by Zhang CX Ge ZM Cheng TM Li RT Article IDs Erowid RefID: 7916 PubMedID: 16412637 Collections Hofmann Collection MDMA Collection All References	Abstract A series of highly sterically hindered secondary amine analogues of pyridylmethylamine 7a-f, 8a-c and positional isomeric analogues of ABT-594 9a-c were synthesized and evaluated for their in vivo analgesic activity. The compounds 7a and 7d show potent analgesic activity and lower toxicity. Some interesting structure-activity relationships have been revealed.
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