Erowid.org: Erowid Reference 8134 : Toward a Comparative Overview of Dependence Potential and Acute Toxicity of Psychoactive Substances Used Nonmedically : Gable RS

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Gable RS. “Toward a Comparative Overview of Dependence Potential and Acute Toxicity of Psychoactive Substances Used Nonmedically”. Am J Drug Alcohol Abuse. 1993;19(3):263-81. <a name="ref">Gable RS.</a> <a href="/references/8134">"Toward a Comparative Overview of Dependence Potential and Acute Toxicity of Psychoactive Substances Used Nonmedically"</a> <i>Am J Drug Alcohol Abuse</i>. 1993;19(3):263-81.
Text Abstract (this page) Full Text - English (private) Show Articles by Gable RS Article IDs Erowid RefID: 8134 PubMedID: 8213692 Collections Hofmann Collection MDMA Collection All References	Abstract A procedure is outlined for comparing dependence potential and acute toxicity across a broad range of abused psychoactive substances. Tentative results, based on an extensive literature review of 20 substances, suggested that the margin of safety 'therapeutic index' varied dramatically between substances. Intravenous heroin appeared to have the greatest risk of dependence and acute lethality oral psilocybin appeared to have the least. Hazards due to behavioral deficits, perceptual distortion, or chronic illness were not factored into the assessments.
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