Erowid.org: Erowid Reference 859 : EMIT-d.a.u. monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) : Poklis A, Fitzgerald RL, Hall KV, Saady JJ

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Poklis A, Fitzgerald RL, Hall KV, Saady JJ. “EMIT-d.a.u. monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA)”. Forensic Sci Int. 1993;59(1):63-70. <a name="ref">Poklis A, Fitzgerald RL, Hall KV, Saady JJ.</a> <a href="/references/859">"EMIT-d.a.u. monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA)"</a> <i>Forensic Sci Int</i>. 1993;59(1):63-70.
Show Articles by Poklis A Fitzgerald RL Hall KV Saady JJ Article IDs Erowid RefID: 859 PubMedID: unknown Collections Hofmann Collection MDMA Collection All References	Abstract The cross-reactivity, stereoselectivity and clinical performance of the EMIT-d.a.u. monoclonal amphetamine/methamphetamine immunoassay (EM) for the detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) in urine was evaluated. The cut-off concentrations of racemic MDA and MDMA were found to be approximately 800 ng/ml and 3000 ng/ml, respectively. The EM assay demonstrated a high selectivity for the S(+) isomer of both MDA and MDMA. Urines collected over a 24-h period from rats administered 20 mg i.v. racemic MDMA were all positive when analyzed by the EM assay. The EM was found vastly superior to the EMIT d.a.u. polyclonal amphetamine/methamphetamine assay for the detection of MDA and MDMA. The EM assay displayed sufficient sensitivity for detection of these drugs following clinical intoxication.
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