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Krupitsky E, Nunes EV, Ling W, Illeperuma A, Gastfriend DR, Silverman BL.
“Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial”.
Lancet. 2011 Apr 02;377(9776):1506-13.
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Abstract
Opioid dependence is associated with low rates of treatment-seeking, poor adherence to treatment, frequent relapse, and major societal consequences. We aimed to assess the efficacy, safety, and patient-reported outcomes of an injectable, once monthly extended-release formulation of the opioid antagonist naltrexone (XR-NTX) for treatment of patients with opioid dependence after detoxification.
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