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Loi B, Zloh M, De Luca MA, Pintori N, Corkery J, Schifano F.
“4,4'-Dimethylaminorex (4,4'-DMAR; Serotoni) misuse: A Web-based study”.
Hum Psychopharmacol. 2017 May 28;32(3).
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Abstract
BACKGROUND:
4,4'-DMAR (4,4'-dimethylaminorex; Serotoni) is a potent stimulant drug that has recently been associated with a number of fatalities in Europe. Over the last few years, online communities have emerged as important resources for disseminating levels of technical knowledge on novel psychoactive substances.
OBJECTIVE:
Analysing the information provided by the fora communities on 4,4'-DMAR use, additionally critical reviewing the available evidence-based literature on this topic.
METHODS:
Different website drug fora were identified. A critical review of the existing evidence-based literature was undertaken. Individuation and analysis of qualitative data from the identified website fora were performed.
RESULTS:
The combined search results identified six website fora from which a range of qualitative data on recurring themes was collected. These themes included routes of administration and doses; desired effects; adverse effects; comparison with other drugs; association with other drugs; medications self-administered to reverse 4,4'-DMAR action; overall impression; and provision of harm-reduction advice.
CONCLUSIONS:
Although being characterized by a number of methodological limitations, the social networks' Web monitoring approach (netnography) may be helpful to better understand some of the clinical and psychopharmacological issues pertaining to a range of novel psychoactive substances, including 4,4'-DMAR, for which only extremely little, if any, scientific knowledge is available.
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