Erowid References Database
Peroutka SJ, Kuhar MJ.
“Autoradiographic localization of 5-HT1 receptors to human and canine basilar arteries”.
Brain Research. 1984;310:193-196.
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Abstract
Autoradiographic techniques were used to identify serotonergic binding sites in human and canine basilar artery segments. 5-HT1 but not 5-HT2, receptors could be localized to the medial layer of the vascular wall using both [3H]LSD and [3H]5-HT. The identification of 5-HT binding sites in human and canine basilar arteries provides anatomical evidence that the 5-HT1 receptor mediates vasoconstriction in these major intracranial vessels.
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